
The World’s First LIVING Brain Prosthetic
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What is ni2o?
NEURON INPUT TO OUTPUT
ni2o is a US-based company working to cure neurodegenerative diseases, like Alzheimer’s, Parkinson’s and ALS, with AI and brain-tech (BCI).

ni2o’s Purpose
We exist to restore human dignity and ability to those suffering with debilitating brain disorders. Nowhere is this need more critical than Alzheimer’s, where patients and families face an overwhelming burden and the healthcare system strains under unsustainable costs. With the global population of those over 60 expected to more than double by 2050, the challenge is clear: without bold innovation, societies cannot provide the care these patients deserve. ni2o is delivering that innovation to shift Alzheimer’s from inevitable decline to early detection, better management, and ultimately reversal.
Our Strategy
We are building a continuum of brain health solutions that starts with prevention and leads to treatment: 1. Ultra-Early Detection (4cyte AI): Proprietary software that identifies signs of Alzheimer’s years before clinical symptoms appear, giving families, physicians, and researchers the ability to act earlier than ever. 2. Continuous Monitoring and Non-Invasive Stimulation (tKIWI): A wearable, EEG-like headcap that records brain activity, supports ongoing monitoring, and enables non-invasive early interventions. 3. Minimally Invasive Therapy (KIWI Micro-Implant): A transformative alternative to today’s high-risk neurosurgical procedures. KIWI is designed as a micro-implant capable of safely restoring brain function, opening the door to treatments that are accessible, scalable, and cost-effective.
Our Focus
Our Focus We begin where the need is greatest: Alzheimer’s disease, a condition with no cure, skyrocketing prevalence, and devastating economic impact. From this foundation, our platform naturally extends to Parkinson’s, ALS, and related neurodegenerative conditions, where patients face similar gaps in early detection, continuous monitoring, and safe therapeutic options.
in Summary
ni2o is advancing a new paradigm for brain health, starting with Alzheimer’s. Through AI-enabled detection, real-time monitoring, and minimally invasive treatment, our mission is bold but clear: restore the brain, restore the person, restore dignity.
Latest News
Advancing Neuromorphic Computing : Mixed-Signal Design Techniques Leveraging Brain Code Units and Fundamental Code Units
April 5, 2024Explore the latest insights into computing’s future with ni2o’s new publication on the Brain Code Unit (BCU) and Fundamental Code Unit (FCU). Discover the innovative integration of neuroscience principles and computational design techniques. Dive into this thought-provoking exploration of emerging...
Comparative analysis of energy transfer mechanisms for neural implants
January 17, 2024Review ni2o’s analysis of energy transfer methods and various implant technologies, including our very own KIWI! Abstract As neural implant technologies advance rapidly, a nuanced understanding of their powering mechanisms becomes indispensable, especially given the long-term biocompatibility risks like oxidative...
Ni2o Showcased at Dubai’s Artificial Intelligence Summit
February 27, 2023Dr. Howard showcases ni2o, Inc.’s mission to eradicate neurodegenerative diseases at Dubai’s Artificial Intelligence Summit in 2021. “One of the world’s leading figures in Artificial Intelligence, the renowned brain and cognitive scientist Newton Howard, PhD., will be at The Artificial Intelligence and...
Tech Tribune awards ni2o, inc. Top Tech Startup of 2022
May 3, 2022Dr. Howard is featured as the founder of ni2o, inc. in the 2022 Top Tech Startups of Providence, RI. To learn more about the inception of ni2o, inc. and the challenges Dr. Howard had to overcome as the...
Researchers Have Developed a Brain-Computer Interface That Adds a Soundtrack to Your Life
February 17, 2022“The public currently perceives music predominantly as a medium for entertainment, but music has a much bigger footprint in human history than this. Historically, it’s served many important roles in society, from social cohesion to mother-infant bonding to healing,” say...
Virtual Reality is being used in exciting ways to treat anxiety and depression
February 8, 2022According to a Mashable article on a study of the efficacy of VR treatment for depression and anxiety, “This type of immersive therapy is a viable and potentially revolutionizing method to treat certain mental health conditions. A blend of VRET...
How Tomagatchi Hacked the Human Brain
February 4, 2022According to an article from Nerdist, “A team of scientists from the University of Cambridge has used the ‘mini brains’ to analyze serious maladies like lateral sclerosis and even dementia. Something they were able to do thanks to stem cells...
Lab Grows “Mini Brains” to Study Neurodegenerative Disease
February 1, 2022According to an article from Nerdist, “A team of scientists from the University of Cambridge has used the ‘mini brains’ to analyze serious maladies like lateral sclerosis and even dementia. Something they were able to do thanks to stem cells...
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